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NEW YORK — Coronavirus deaths are rising in nearly two-thirds of American states as a winter surge pushes the overall toll toward 400,000 amid warnings that a new, highly contagious variant is taking hold.

As Americans observed a national holiday Monday for the Rev. Dr. Martin Luther King Jr., New York Gov. Andrew Cuomo pleaded with federal authorities to curtail travel from countries where new variants are spreading.

Referring to new versions detected in Britain, South Africa and Brazil, Cuomo said: “Stop those people from coming here.... Why are you allowing people to fly into this country and then it’s too late?”

The U.S. government has already curbed travel from some of the places where the new variants are spreading — such as Britain and Brazil — and recently it announced that it would require proof of a negative COVID-19 test for anyone flying into the country.

But the new variant seen in Britain is already spreading in the U.S., and the Centers for Disease Control and Protection has warned that it will probably become the dominant version in the country by March. The CDC said the variant is about 50% more contagious than the virus that is causing the bulk of cases in the U.S.

While the variant does not cause more severe illness, it can cause more hospitalizations and deaths simply because it spreads more easily. In Britain, it has aggravated a severe outbreak that has swamped hospitals, and it has been blamed for sharp leaps in cases in some other European countries.

As things stand, many U.S. states are already under tremendous strain. The seven-day rolling average of daily deaths is rising in 30 states and the District of Columbia, and on Monday the U.S. death toll surpassed 398,000, according to data collected by Johns Hopkins University — by far the highest recorded death toll of any country in the world.

Ellie Murray, an assistant professor of epidemiology at the Boston University School of Public Health, said cases have proliferated in part because of gatherings for Christmas and New Year — and compounded previous surges from Thanksgiving and the return of students to schools and universities in the fall.

The pace of any further spread will depend on whether those who did gather with family and friends quarantined afterward or went back to school or work in person, she said.

In Los Angeles, some pollution limits on the number of cremations have been suspended for at least 10 days to deal with a backlog of bodies at hospitals and funeral homes.

One of the states hardest hit during the recent surge is Arizona, where the rolling average has risen over the past two weeks from about 90 deaths per day to about 160 per day on Jan. 17.

“It’s kind of hard to imagine it getting a lot faster than it is right now, because it is transmitting really fast right now,” said Dr. Joshua LaBaer, director of the Biodesign Institute research center at Arizona State University. “But there is some evidence that Thanksgiving didn’t help things.”

Amid the rise in cases, a vast effort is underway to get Americans vaccinated — what Cuomo called “a footrace” between the vaccination rate and the infection rate. But the campaign is off to an uneven start. According to the latest federal data, about 31.2 million doses of vaccine have been distributed, but only about 10.6 million people have received at least one dose.

In some cases, vaccine supplies thus far do not meet demand. More than 172,000 people in Missouri’s St. Louis County have registered for the vaccine, but the local health department so far has only received 975 doses, said County Executive Sam Page.

In California, the most populous state, counties are pleading for more vaccine as the state tries to reduce a high rate of infection that has led to record numbers of hospitalizations and deaths.

Although the state last week said anyone age 65 and older can start receiving the vaccine, Los Angeles County and some others have said they don’t have enough to immunize so many people. They are concentrating on protecting health care workers and the most vulnerable elderly in care homes first.

On Monday, the superintendent of the Los Angeles Unified School District sent a letter asking for state and county authorization to provide vaccinations at schools for staff, local community members — and for students once a vaccine for children has been approved.

The death rate from COVID-19 in Los Angeles County — an epicenter of the U.S. pandemic — works out to about one person every six minutes. On Sunday, the South Coast Air Quality Management District suspended some pollution-control limits on the number of cremations for at least 10 days in order to deal with a backlog of bodies at hospitals and funeral homes.

Numbers improving in Pa., locally

While the COVID-19 infection numbers are rising nationwide, figures reported Monday by the state Department of Health were more positive.

The state reported 3,667 new cases Monday, the lowest figure since Jan. 3 — and, before that, Nov. 8. In Mercer County, the state reported 22 new cases, the least since Dec. 27, when the county also had 22 new cases.

The last time Mercer County had fewer than 22 new cases in a single day was Oct. 31, with seven.

Hospital demand decreasing in Pa.

The state had 4,582 hospitalized COVID-19 patients Monday, continuing a steady decline. Over the last two weeks, the rolling average of hospitalizations has been 5,134, almost 600 patients higher than Monday’s single-day number.

The number of patients on ventilators, 583, continued to decline. The 14-day rolling average is 628.

There are fewer than 1,000 patients in intensive care units, with 950. The rolling daily average of available ICU beds declined slightly over the last two days, from 633.1 on Jan. 16 to 629 Monday, but the decrease is due largely to hospitals shutting down ICU beds.

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